Semaglutide COA: Third-Party Lab Report | Healio

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Semaglutide COA (Certificate of Analysis)

This is the certificate of analysis for the current Semaglutide 10 mg batch, tested by Quantum Life Sciences, Portland, ME. Purity is measured by HPLC, identity is confirmed by mass spectrometry and endotoxins are checked by the LAL method. The summary and the full result table are below. The original certificates are shown on the research page.

Semaglutide for sale · All COAs

Semaglutide 10 mg test results

Certificate numberCOA-2026-SEMA10-0507
BatchHEALIO-SEMA10-2607
Lot numberSEMA10-260621-07
Labeled content10 mg
Received by lab18 June 2026
Analysis date23 June 2026
Purity (HPLC)99.4%
Identity (ESI-MS)Confirmed, conforms to the reference standard (4113.58)
Mass found10.11 mg (labeled 10 mg)
Endotoxins (LAL)Under 0.5 EU/mg (limit 5 EU/mg)
CAS number910463-68-2
FormulaC187H291N45O59, 4113.58 g/mol
TestSpecificationResult
AppearanceWhite to off-white lyophilized powderConfirmed
SolubilitySoluble in waterConfirmed
Identity (ESI-MS)Conforms to reference standard (4113.58)Confirmed
Purity (HPLC)98.0% or higher99.4%
Related substances (single / total)1.0% / 2.0% or lower0.3% / 0.6%
Water (Karl Fischer)8.0% or lower4.3%
Acetate / TFA content10.0% or lower6.9%
Assay95.0% to 105.0%99.0%
Endotoxins (LAL)5 EU/mg or lowerUnder 0.5 EU/mg

Purity and quantity by RP-HPLC with UV detection, identity by ESI-MS, endotoxins by LAL (USP <85>). Results relate only to the sample tested.

Semaglutide 5 mg test results

Certificate numberCOA-2026-SEMA5-0506
BatchHEALIO-SEMA5-2606
Lot numberSEMA5-260620-06
Labeled content5 mg
Received by lab18 June 2026
Analysis date23 June 2026
Purity (HPLC)99.3%
Identity (ESI-MS)Confirmed, conforms to the reference standard (4113.58)
Mass found5.06 mg (labeled 5 mg)
Endotoxins (LAL)Under 0.5 EU/mg (limit 5 EU/mg)
CAS number910463-68-2
FormulaC187H291N45O59, 4113.58 g/mol
TestSpecificationResult
AppearanceWhite to off-white lyophilized powderConfirmed
SolubilitySoluble in waterConfirmed
Identity (ESI-MS)Conforms to reference standard (4113.58)Confirmed
Purity (HPLC)98.0% or higher99.3%
Related substances (single / total)1.0% / 2.0% or lower0.4% / 0.7%
Water (Karl Fischer)8.0% or lower4.4%
Acetate / TFA content10.0% or lower7.1%
Assay95.0% to 105.0%98.6%
Endotoxins (LAL)5 EU/mg or lowerUnder 0.5 EU/mg

Purity and quantity by RP-HPLC with UV detection, identity by ESI-MS, endotoxins by LAL (USP <85>). Results relate only to the sample tested.

How to read this Semaglutide certificate

  • Purity (HPLC). The share of the powder that is the target compound rather than related substances. A figure close to the top of the range is only meaningful next to a specification, which is why both are shown.
  • Identity (ESI-MS). Mass spectrometry weighs the molecule. A match to the reference mass is what shows the vial holds Semaglutide and not something else.
  • Mass found against labeled content. The amount measured in the vial next to the amount on the label.
  • Endotoxins (LAL). A bacterial contamination marker, reported in EU per mg against a limit.
  • Batch and lot. The lot number on your vial is the number printed on the report, so you can check one against the other.

For a longer walk through every line, read how to read a certificate of analysis and peptide purity testing.

Semaglutide research tools

Semaglutide COA FAQ

What is the Semaglutide COA?

A certificate of analysis is the lab report for one batch of a product. The Semaglutide report, certificate COA-2026-SEMA10-0507, was issued by Quantum Life Sciences on 23 June 2026 for batch HEALIO-SEMA10-2607, lot SEMA10-260621-07.

What purity did the Semaglutide batch test at?

The batch measured 99.4% purity by HPLC. The specification is 98.0% or higher.

How is Semaglutide identity confirmed?

By mass spectrometry (ESI-MS). The result on this certificate is: Confirmed, conforms to the reference standard (4113.58). Purity tells you how clean the powder is, and identity tells you it is the compound on the label.

Does this COA cover every Semaglutide size?

This certificate covers the 10 mg vial from batch HEALIO-SEMA10-2607. The lot number on a vial ties to its own report, so match the number on your vial to the certificate.

Where can I buy Semaglutide with a COA?

Healio publishes the certificate before you order. Semaglutide is sold for laboratory research use only, from the United States.

Healio Peptides supplies research compounds for laboratory use only. They are not for human or veterinary use.